Why it is necessary to treat cervical dysplasia (erosion)

At present Human Papillomavirus (HPV) is considered to be the main etiological factor of erosion and cervical cancer development (P. I. Kovchur, I. E. Bakhlaev. "Alokin-alpha in complex therapy for Human Papillomavirus infection in women with cervical diseases, Petrozavodsk State University, 2008, page 1). It is important to notice that cervical cancer is not only a medical but also sociodemographic problem. According to modern epidemiological studies HPV reverse the development of cervical cancer in 99.7%, cancer of vulva, vagina, penis, prostate and testis in 10-30%, cancer of the larynx and oral cavity in 10-30% of cases.

The incidence of erosive processes and cervical cancer (CC) varies from 10 to 40 per 100 thousand of female population. Half of patients die within the first year after diagnosis (P. I. Kovchur, I. E. Bakhlaev. "Alokin-alpha in complex therapy of Human Papillomavirus infection in women with cervical diseases, Petrozavodsk State University, 2008, page 1). The development of erosive lesions depends on the immune status of the patient, the type of Human Papillomavirus infection, comorbidity and possessing the additional bacterial infection.

Cervical cancer is preceded by cervical intraepithelial neoplasia, which are caused by the abnormal control of cell proliferation. But the abnormal control of cell proliferation is the result of HPV activities together with additional bacterial infection in these cells and also without it.

The ability to indefinitely long persistence in the body of the patient is due to the specifics of these viruses life strategies, based on blocking mechanisms of innate and adaptive antiviral immunity. Using different techniques of molecular mimicry, suppression of immune cells activity, human papilloma viruses protect contaminated epithelial cells from the destruction of T-lymphocytes and natural killers, unimpeded replication of the viral genome and infection of new host cells.

Recently a number of fertility disorders as infertility have been identified, which are associated with infection of the cervix with HPV. Therefore an important step in the prevention of erosion and malignant cervical neoplasm is early diagnosis and effective treatment of erosive cervical lesions with HPV. But, despite the proven viral etiology of cervical cancer, the presence of a large number of clinical, subclinical and latent forms of this disease, high contagiousness and the recurrence of HPV infection, there are no specific drugs to suppress HPV, which makes search for new ways to therapy of this disease.

The lack of treatment or incorrect treatment of patients with Human Papillomavirus infection in women increases the development of cervical erosion. Further progression of the disease leads to malignancy erosive process and consequently the development of dysplasia and cervical cancer.

Distribution of PV types with high oleaginosa risk

Ask your gynecologist if he (she) has an experience in treatment of human papillomavirus infection to the complete removal of human papilloma virus from the body?