ALLOKIN-ALPHA HOME-MADE ANTIVIRUS NEW-GENERATION DRUG FOR HERPES AND PAPILLOMA VIRAL INFECTION (HPV) TREATMENT FAREWELL TO VIRUS! RUEnglishUA
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A new treatment way of Herpes Zoster with Allokin-alpha

All the information contained on this informational resource is intended exclusively for practitioners and cannot be used by the site visitors for self-diagnosing and prescribing treatment without a previous consultation with the doctor.

One of the new approved treatment of Herpes Virus infections is a national antiviral drug Allokin-alpha.
In comparison with acyclovir (AC) the tests showed the safety and clinical efficiency of Allokin-alpha in the treatment of patients with Herpes Zoster.

The following parameters were weighted in the analysis of the therapy results:

  • hospitalization and disease duration;
  • pain and rash duration;
  • frequency of complications as an eye damage in ganglioneuritis of the 1-st branch of trigeminal nerve.

The parenteral use of Allokin-alpha did not cause any allergic or other adverse reactions, it was well accepted and convenient in use, it can be combined with other drugs.

When Allokin-Alfa was included in the treatment of patients with Herpes Zoster, Ophthalmic Herpes did not have a progress at all (if it had not developed before the treatment with Allokin-alpha), and 30% of the patients had a regression of eye incipient lesion.

HZ with eye lesion follows in the course of lymphopenia (secondary immune deficiency), but after a combined therapy (AC + Allokin-alpha) the number of lymphocytes increased by 50%, thus the immuno-biological resistance of the body had been increasing.

The researches results of F. I. Ershov and others (2003) in the treatment with Allokin-alpha in patients with Genital Herpes have identified the increase of cytokines production, favoring the formation of TX1-immune response mostly, which is very important in rehabilitation of the body from Herpes Viruses (F. I. Ershov et al., 2003; V. A. Isakov. and others, 2006).

Allokin-alpha had induced the synthesis of anti-inflammatory cytokine IL-10 that is the answer for the anti-inflammatory and analgesic effect of the drug in the treatment of patients with HZ. These influence results of Allokin-alpha on the interferon status, cytokine profile and the expression of cytokine genes allow to explain the high clinical efficiency of Herpes Zoster treatment with Allokin-alpha.

The influence of treatment with Allokine-alpha in patients with Herpes Zoster on
the duration of main clinical symptoms


Index Therapy duration of symptoms (days)
 

Monotherapy with
aciclovir
(n=15)

Aciclovir +
Allokin-alpha (n=20)

Admission duration

12,4

10,5

Disease duration

17,7

16

Pain, burning duration

22

14

Duration of rash period, including:
- phase of vesicular-pustular elements

- phase of crusts

16,8

15,6

9,7

8,9

7,1

6,7

Frequency of complications as an eye damage at the time of hospitalization (%)

60%*

 

  50%

Frequency of complications as an eyes damage in the end of hospitalization (%)

86%*

35% (% reduction of eye damage)

Duration of clinical symptoms of eye damage

14*

11,1

Note: * - p < 0,05

Including Allokin-alpha into a complex HZ therapy, has contributed to a significant reduction in the duration of pain and burning sensation by 1/3. It allowed to avoid any complication of HZ in the form of eye lesions and the clinical symptoms of already developed Ophthalmic Herpes had passed quickly.

Allokin-alpha can be recommended for the wide practical application as a drug of choice in the complex therapy of Herpes Zoster..

Read more:

Ask your gynecologist if he (she) has an experience in treatment of human papillomavirus infection to the complete removal of human papilloma virus from the body?

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