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The background of Herpes Zoster
The infection caused by the varicella - zoster virus (VZV) is implemented by droplets. The primary manifestation of infection at young age is caused by the clinical picture of varicella (V), followed by a latent stage of virus persistence in the body (macrophages of periferic blood, liver, neurons, etc.), and under certain conditions there is a reactivation of the virus with manifestation of different clinical forms, one of which is Herpes Zoster (HZ) (I. G. Belianska, 1996; A. G. Kolomiets, et al., 1992).
The reproduction of Herpes Simplex and Herpes Zoster occurs in polymorphonuclear leukocytes and monocytes. Communication with leukocytes provides the virus protection against the factors of humoral immunity and creates real preconditions for further dissemination (I. F. Barinsky, 2004; A. G. Kolomiets, et al., 1992). Virus HZ is also found in erythrocytes, in which the formation of inclusionsare has been formed. It is shown that more than half of the cases of HZ is related to the patients older than 50 years (V. A. Isakov et al., 2006; N. V. Sizova et al., 2003).
It is known that the reaction of the humoral immunity is not decisive in the suppression of relapse of HZ, and only partially protects against exogenous virus. The reactivation risk of VHZ increases sharply in individuals with immunodeficiencies of different origins (V. A. Isakov et al., 2004; A. G. Rakhmanova, et al., 1997). The clinical picture of HZ syndrome of postzoster neuralgia (PZN) has a great importance, which can occur in 20-30% of patients and can persist from 3 months to several years after suffering from HZ, which attaches the importance to post-infectious immune-mediated mechanisms in the genesis of development.
Ask your gynecologist if he (she) has an experience in treatment of human papillomavirus infection to the complete removal of human papilloma virus from the body?
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